Glucagon-like peptide-1 (GLP-1) is a hormone that both acts as a satiety signal in response to food intake and also stimulates insulin release and inhibits glucagon secretion in response to food ingestion. Researchers at Terns Pharmaceuticals Inc. have presented preclinical data on TERN-601, a GLP-1 receptor (GLP-1R) agonist, in humanized GLP-1R (hGLP-1R) mouse models.