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» VVD-133214, an allosteric inhibitor of WRN helicase with promising efficacy in MSI-H cancer models
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Cancer
VVD-133214, an allosteric inhibitor of WRN helicase with promising efficacy in MSI-H cancer models
May 14, 2024
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Researchers from Vividion Therapeutics Inc. and partner Roche Holdings AG have published the discovery and preclinical characterization of the novel covalent allosteric inhibitor of WRN, VVD-133214 (RO-7589831).
BioWorld Science
Cancer