The controversy about the origins of the SARS-CoV-2 virus and the accusations that it escaped from the Wuhan Institute of Virology, or even that it was deliberately engineered there, could – possibly – be brought to a close by two papers published July 26, 2022.
Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Abbvie, Biogen, Cidara, Editas, ERC, Genuine, GBT, GSK, Inflarx, Ionis, LFB, Novavax, Sirnaomics.
An expert panel of Japan’s Ministry of Health, Labour and Welfare (MHLW) pushed back on recommending conditional approval for a second time for Shionogi & Co. Ltd.’s orally administered COVID-19 antiviral 3CL protease inhibitor, S-217622, also known as ensitrelvir.
Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Astrazeneca, B.More, Bridgebio, Hookipa, Lepu, Matinas, Medexus, Qbiotics, Veru.
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Aligos, Ashvattha, Inmed, Nanoscope, Philogen, Revelation, Revive, Sling.
Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Blue Water, Bridgebio, HDT, Innate, Neurofront, Novaremed, Pharmacyte, Sanofi, Valneva, Zyversa.
Since the isolation of SARS-CoV-2 and the study of its infection mechanisms, scientists have been trying to understand how this virus accesses the brain and produces neurological symptoms. The receptor necessary for the virus to enter the cell by endocytosis (the receptor for angiotensin-converting enzyme 2, ACE2) is only expressed by some neurons and is hardly detected in the brain.