HSK-26784 shows efficacy in multiple B lymphocyte-derived malignancy models June 30, 2020 No Comments
Discovery and preclinical characterization of novel dual inhibitor of LSD1-HDAC6, JBI-802 June 29, 2020 No Comments
New peripheral 5-HT2A antagonists for NAFLD treatment by structural modification of pimavanserin June 19, 2020 No Comments
Y220X mutations impairing the thermostability of p53 can be targeted with small-molecule stabilizers June 15, 2020 No Comments
Optimization of a spiroindolinone-based tankyrase inhibitor blocking WNT pathway in colon cancer June 12, 2020 No Comments
New D peptide blocking TIGIT/PVR binding for cancer immunotherapy even in anti-PD-1-resistant tumors June 8, 2020 No Comments
Design and characterization of novel topoisomerase II poisons with improved drug-like profile June 8, 2020 No Comments
Selective TREK channel activator alleviates pain in mice without opioid-like adverse effects June 5, 2020 No Comments
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