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BioWorld - Sunday, October 19, 2025
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3D rendering of 2-Arachidonoylglycerol (2-AG) endocannabinoid neurotransmitter molecule

ECNP 2025: Endocannabinoids have metabolic role in mental health

Oct. 16, 2025
By Anette Breindl
No Comments
At the 2025 European College of Neuropsychopharmacology (ECNP) Congress in Amsterdam this week, researchers presented new findings on the role of endocannabinoids in stress, addiction … and the integrity of the blood-brain-barrier.
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Microscope on Japan flag

Bio Japan 2025: Nobel Prizes invigorate Japan’s bio industry

Oct. 14, 2025
By Tamra Sami
No Comments
Bio Japan 2025 was abuzz with the news that Japan has once again snagged the Nobel Prize in Physiology or Medicine, with Shimon Sakaguchi winning for his discovery of a subtype of CD4-expressing T cells that affect the immune response. Earlier today, Susumu Kitagawa snatched the second Nobel Prize for Japan, this time in chemistry. Both Nobel Prize winners were professors at Kyoto University.
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Illustration of DNA double helixes inside drop of blood
Hematologic

Gene therapy for hemophilia stalls but doesn’t stop at ESGCT

Oct. 13, 2025
By Mar de Miguel
No Comments
While recent advances in gene therapy have offered unprecedented options for patients with hemophilia, new data presented at the 32nd Annual Congress of the European Society of Gene and Cell Therapy (ESGCT), held in Seville Oct. 7-10, revealed persistent concerns regarding the durability of these treatments and their potential liver toxicity.
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Illustration of DNA double helixes inside drop of blood
Hematologic

Gene therapy for hemophilia stalls but doesn’t stop at ESGCT

Oct. 10, 2025
By Mar de Miguel
No Comments
While recent advances in gene therapy have offered unprecedented options for patients with hemophilia, new data presented at the 32nd Annual Congress of the European Society of Gene and Cell Therapy (ESGCT), held in Seville Oct. 7-10, revealed persistent concerns regarding the durability of these treatments and their potential liver toxicity.
Read More
Illustration of human body surrounded by DNA, cell and drug icons
Drug design, drug delivery & technologies

At ESGCT, emerging technologies for in vivo therapies

Oct. 9, 2025
By Mar de Miguel
No Comments
The transition from complex and costly ex vivo strategies to platforms that enable direct cellular intervention within the body, known as in vivo therapies, is marking a paradigm change in the field of gene and cell therapies by simplifying manufacturing, improving tissue targeting and expanding clinical access to treatments.
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Microscope on Japan flag

Bio Japan 2025: Nobel Prizes invigorate Japan’s bio industry

Oct. 8, 2025
By Tamra Sami
No Comments
Bio Japan 2025 was abuzz with the news that Japan has once again snagged the Nobel Prize in Physiology or Medicine, with Shimon Sakaguchi winning for his discovery of a subtype of CD4-expressing T cells that affect the immune response. Earlier today, Susumu Kitagawa snatched the second Nobel Prize for Japan, this time in chemistry. Both Nobel Prize winners were professors at Kyoto University.
Read More
Red CAR T cell on blue blackground
Drug design, drug delivery & technologies

ESGCT 2025: Redefining CAR T cells across cancer and autoimmunity

Oct. 8, 2025
By Mar de Miguel
No Comments
As the many challenges facing cell therapies are being addressed, the CAR T field continues to evolve beyond its original design of T cells engineered to target hematological malignancies. During the 32nd Annual Congress of the European Society of Gene and Cell Therapy (ESGCT), held in Seville Oct. 7-10, several studies showed how this technology is being redefined as programmable and adaptable immune cells with expanded functional versatility.
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Noble Chemistry illustration
Drug design, drug delivery & technologies

Chemistry Nobel’s applications could include biopharma, though translation is slow

Oct. 8, 2025
By Anette Breindl
No Comments
The 2025 Nobel Prize in Chemistry “is a story full of holes, but with enormous capacity to absorb all your attention,” Heiner Linke told reporters. “And other things.” Linke is Chair of the Nobel Committee for Chemistry. On Oct. 8, 2025, the committee announced that it has awarded the 2025 Nobel Prize in Chemistry to Susumu Kitagawa, Richard Robson and Omar Yaghi “for the development of metal-organic frameworks” (MOFs).
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Nobel Prize Treg illustration
Shared by industry scientists

2025 Nobel honors autoimmunity discoveries

Oct. 7, 2025
By Anette Breindl
No Comments
The Nobel Committee announced today that it has awarded the 2025 Nobel Prize in Physiology or Medicine to three scientists for their discovery of regulatory T cells, which are a critical part of the way the body prevents autoimmune attacks.
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Cancer diagnostic illustration
Cancer

New AI model can assign certainty, or uncertainty, to predictions

Oct. 7, 2025
By Marian (YoonJee) Chu
No Comments
A team of U.S. and South Korean researchers have developed an AI model called MSI-SEER that can not only predict microsatellite instability-high (MSI-H) tumors based on tissue slides, but also flag “what it does not know.” “Have you ever asked ChatGPT anything, and the response was, ‘I don’t know?’” Cheong Jae-ho asked during an interview with BioWorld. “Probably not, and that is the problem with AI now.”
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