Heteroaryl compounds acting as interleukin-1 receptor-associated kinase 4 (IRAK-4) inhibitors are described in a recent Accro Bioscience (HK) Ltd. patent. They are reported to be useful for the treatment of endometriosis, systemic lupus erythematosus, multiple sclerosis, psoriasis, rheumatoid arthritis, primary central nervous system and diffuse large B-cell lymphoma.