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BioWorld - Tuesday, May 26, 2026
Home » Topics » Clinical

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Ebola virus in petri dish with lab, scientist background

Work underway on vaccines, antivirals against rare Bundibugyo Ebola outbreak

May 26, 2026
By Nuala Moran
No Comments
Less than two weeks after the outbreak was officially declared, animal studies of a newly designed vaccine against the Bundibugyo Ebola virus are now underway in the U.S. and U.K., and the Serum Institute of India is standing ready to manufacture the vaccine for clinical trials. If the animal tests are positive, the vaccine will be ready for clinical trials in two to three months.
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Syringes in virus cell; Lilly, Curevo, Limmatech, Vaccine Company   logos

Lilly buys three vaccine makers; PCSK9 base editor shows promise

May 26, 2026
By Karen Carey
No Comments
As the most active biopharma acquirer of 2026, Eli Lilly and Co. offered to buy three vaccine companies for up to $3.8 billion combined, while it simultaneously released positive early clinical results of a gene editing medicine brought into the fold last year through its buyout of Verve Therapeutics Inc.
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Illustration of cancer in the pancreas

MEK inhibitor delivers 17.3-month OS for pancreatic cancer

May 22, 2026
By Karen Carey
No Comments
Immuneering Corp. reported a median overall survival of 17.3 months in first-line metastatic pancreatic cancer patients treated with its MEK inhibitor atebimetinib (IMM-1-104) plus modified gemcitabine/nab-paclitaxel in a phase IIa trial. Mizuho analyst Graig Suvannavejh called the results “astounding … easily beating current standard-of-care treatments.”
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Lung infection caused by bacteria Pseudomonas aeruginosa

Infex has positive phase IIa data in bronchiectasis; preps for next trial

May 21, 2026
By Nuala Moran
No Comments
Infex Therapeutics Ltd. has published positive phase IIa data for its lead program, RESP-X, in the treatment of exacerbations of chronic respiratory infections caused by Pseudomonas aeruginosa and is now laying the ground for phase IIb development, after raising £4.3 million (US$5.8 million) in new capital.
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Feet on scale and measuring tape

Another Triumph: Lilly’s triple G agonist scores in obesity

May 21, 2026
By Karen Carey
No Comments
Posting another win for its triple G agonist, Eli Lilly and Co. rolled out top-line phase III data from Triumph-1 showing that all doses of retatrutide met primary and key secondary endpoints for obesity, with participants losing on average between 19% and 28.3% of body weight and significantly improving their cardiovascular risk factors.
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Boston Scientific Watchman FLX
EuroPCR 2026

Subgroup analysis of the Champion-AF trial shows age not a factor

May 20, 2026
By Shani Alexander
No Comments
A subgroup analysis of data from Boston Scientific Corp.’s Champion-AF trial, which looked at the outcomes for patients with atrial fibrillation treated with a left atrial appendage closure (LAAC) device compared to direct oral anticoagulants (DOACs), found that the efficacy and safety of LAAC compared to DOAC are not affected by age. The data were presented at the EuroPCR conference in Paris.
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Biosensors International Allegra transcatheter heart valve
EuroPCR 2026

All Women data show Allegra edge in female TAVR patients

May 20, 2026
By Shani Alexander
No Comments
Data from the All Women clinical trial, which looked at the Allegra transcatheter aortic valve replacement (TAVR) system compared to balloon-expandable valves (BEV) in women with aortic stenosis, showed that Allegra delivered lower mean gradients and less prosthesis-patient mismatch than BEVs. The data presented at the EuroPCR conference in Paris was the first randomized head-to-head comparison of different TAVR platforms conducted exclusively in women.
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Hands highlighted with joint pain

Immunovant rises on IMVT-1402 data in difficult-to-treat RA

May 20, 2026
By Jennifer Boggs
No Comments
Shares of Immunovant Inc. (NASDAQ:IMVT) gained 35% after the firm disclosed early but “compelling” data from a phase IIb study testing next-generation FcRn inhibitor IMVT-1402 in patients with difficult-to-treat rheumatoid arthritis (D2T RA), including those whose disease has persisted despite treatment with TNF and JAK inhibitors.
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Oral medication

Vincentage’s oral GLP-1 meets phase III obesity endpoints

May 19, 2026
By Tamra Sami
No Comments
Vincentage Pharma Co. Ltd.’s once-daily oral small-molecule GLP-1 receptor agonist, VCT-220, met the primary endpoints in a pivotal phase III trial in overweight or obese patients in China. Based on the top-line data, the Chengdu, China-based company plans to submit an NDA for chronic weight management to China’s National Medical Products Administration.
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Elixir Medical DynamX
EuroPCR 2026

Elixir Dynamx system sees lower event rates than drug-eluting stent

May 19, 2026
By Shani Alexander
No Comments
Elixir Medical Corp. reported four-year data from the Bioadaptor randomized controlled trial presented at the EuroPCR conference in Paris, which showed that patients with coronary artery disease treated with its Dynamx coronary drug-eluting bioadaptor system experienced significantly lower event rates compared to those treated with Medtronic plc’s Resolute Onyx drug-eluting stent, including reduction in cardiovascular death.
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