LONDON – A vast new body of genomics research has identified thousands of rare genetic variants that are predicted to cause loss of function in protein coding genes, providing novel in vivo models of human gene inactivation.
Keeping you up to date on recent developments in oncology, including: Optoacoustic mesoscopy offers three-dimensional tumor imaging without biopsy; P53 loss leads to immune evasion; Treatment less toxic for Burkitt lymphoma.
Variants in the APOE gene are the strongest genetic risk factor for developing Alzheimer’s disease (AD). Now, researchers at Rockefeller University have demonstrated that APOE variants also affected the risk of progression and metastasis as well as the response to immunotherapy, in melanoma.
Keeping you up to date on recent developments in neurology, including: Noninvasive brain stimulation controls monkeys' choices; Researchers link gene mutation to autism behaviors; Atherosclerosis, AD meet at the myelin; Early roots of ALS visible in teeth.
BioWorld looks at translational medicine, including: SIRPa blockade wakes up macrophages post-infection; Lasting immunity to SARS-CoV-2 looks possible; Atherosclerosis, AD meet at the myelin; T cell aging induces broad senescence; P53 loss leads to immune evasion; Early roots of ALS visible in teeth; SLAPping down MDR gram-negatives; ALK is candidate thinness gene; Can N-BPs become MVP again?
Researchers at Duke University have identified a region in the central amygdala – more often thought of as a processing hub for emotions – that could suppress pain when activated.
Keeping you up to date on recent developments in diagnostics, including: Deep learning algorithm helps to differentiate TBI lesions; Methylation markers in HPV-associated head and neck cancer; The World According to GARP.
Keeping you up to date on recent developments in orthopedics, including: Lab engineers 3D-functional bone tissues; Comparison of early postoperative pain after first vs. second total knee arthroplasty; Vitamin B3 revitalizes energy metabolism in muscle disease; Worldwide IOF-ISCD survey of bone densitometry units published.
Keeping you up to date on recent developments in oncology, including: New LAT1 inhibitor may improve outcomes in cancer as part of combo therapy; Subdividing and conquering PDAC; Cell competition links hyperinsulinemia to cancer; Protons show well in study against alternatives.
Keeping you up to date on recent developments in cardiology, including: Robotic PCI reduces radiation exposure; COVID-19 and cardiovascular problems; Heart attack prevention falls short for stroke, PAD patients; Integrated herpesvirus-6 is pre-eclampsia risk factor.
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