Factor Bioscience Inc. has been awarded a grant by the U.S. Department of Defense to develop next-generation cell therapy candidates using Factor's patented mRNA, cell-reprogramming, and gene-editing technologies.

Biocytocgen Pharmaceuticals (Beijing) Co. Ltd. has entered into an exclusive option and license agreement with Radiance Biopharma Inc., granting Radiance an option to license from Biocytogen a first-in-class fully human anti-HER2/TROP2 bispecific antibody-drug conjugate (BsADC).

CC-chemokine receptor 3 (CCR3) is a member of the G protein-coupled, seven-transmembrane receptor family expressed on mouse eosinophils, basophils, mast cells and mononuclear phagocytes, among others, that plays a role in allergic diseases such as allergic rhinitis.

The IL-6 pathway is involved in atherosclerosis, since its inhibitory targeting reduced atherosclerotic lesions in mouse models.

Researchers from Indian Council of Medical Research and affiliated organizations presented the discovery and preclinical evaluation of OSP-rT2544, being developed for the treatment of salmonella.

A landmark, real-world study in the U.K. has demonstrated that combining whole genome sequencing with clinical data enabled tailored cancer treatment and improved outcomes. At one health care center, having DNA sequence data led to changes from usual standard of care in 25% of cases. “Mostly, [patients] got into clinical trials; some got medicines they wouldn’t have got. Others avoided medicines because their genetic make-up suggested that if they were exposed to the medicines, they would be at risk of harm,” said Mark Caulfield, professor of clinical pharmacology at Queen Mary University of London, who is co-author of a paper outlining the findings in Nature Medicine, Jan 11, 2024.