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BioWorld Science

July 4, 2018

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Data in humans support use of 11C-LSN3172176 for brain AChR M1 PET imaging

Brain infusion of recombinant poliovirus therapy prolongs survival in recurrent glioblastoma

Aslan Pharmaceuticals submits clinical trial authorization

MabVax grants exclusive sublicense to Y-mAbs for neuroblastoma vaccine

Phase II results presented for osimertinib in NSCLC harboring uncommon EGFR gene mutations

Positive topline data presented from phase IIa study of ABX-464

ARCHER 1050 study demonstrates superiority of dacomitinib to gefitinib in advanced NSCLC

Trerief approved in Japan for additional indication

Diagnogreen receives approval for additional indication and dosage in Japan

Updated data for phase I/II study of BMS-986205 plus nivolumab in advanced bladder cancer

JCR initiates phase III trial of JR-401X for SHOX deficiency

Photo-controlled adenosine A2A receptor antagonist may help in the management of Parkinson's disease

Catalent to acquire Juniper Pharmaceuticals

Bionomics presents new nicotinic alpha7 receptor antagonists

Anavex cleared to begin phase IIb/III study of Anavex 2-73 for early Alzheimer's disease

Kalyra Pharmaceuticals patents amphotericin B derivatives as antifungals

Imbruvica approved in Japan for untreated CLL

BeiGene identifies new PI3Kdelta inhibitors

Sorrento acquires Sofusa lymphatic delivery technology platform from Kimberly-Clark

New P2X4 antagonists synthesized by Bayer

Spiramycin approved in Japan for treatment of toxoplasmosis during pregnancy

Titan postpones enrollment in next cohort of phase I/II trial of ropinirole implant

Jiangsu Nhwaluokang Pharmaceutical discovers allopregnanolone prodrugs

Copeptin could be used to diagnose obesity-induced insulin resistance

FDA awards orphan drug designation to N-Rephasin for treatment of anthrax

Evotec closes strategic transaction with Sanofi

FDA approves Xeomin for chronic sialorrhea

CAR-T cell therapy plus allogeneic transplantation in relapsed/refractory B-cell malignancies

WDR47, involved in microtubule dynamics and function, is a candidate gene for heterotaxy syndrome

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