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BioWorld Science

July 8, 2019

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Syndecan-2 increases cell invasiveness in lung adenocarcinoma

PK and safety of a new formulation of nemiralisib inhaled as dry powder in healthy individuals

Antimicrobial peptide LL-37 shows promising efficacy against S. aureus biofilms

Tau-targeted PET with flortaucipir in Alzheimer's disease: evaluation of tau and cognitive changes

Novel PIK3CD gene variant linked to activated PI3Kdelta syndrome

CXCL10 gene promoter -1447A>G polymorphism as a new biomarker of susceptibility to malaria

Rare frameshift mutation in SERPINA3 associated with generalized pustular psoriasis

New target improves metabolism

Chaperone gene therapy delays ALS

Merck & Co., Idenix Pharmaceuticals describe HIV-1 reverse transcriptase/ribonuclease H inhibitors

New hematopoietic prostaglandin D2 synthase inhibitors discovered at GlaxoSmithKline

Gedeon Richter presents vasopressin V1A receptor antagonists

Leukotriene C4 production inhibitors patented by Shaanxi University of Science & Technology

Almirall identifies acetyl-CoA carboxylase inhibitors

New wound-healing antibacterial EBC-1013 presented

Focus V approved in China for soft tissue sarcoma

Eisai and University of Dundee collaborate on PROTAC research

Boehringer Ingelheim studies safety and pharmacokinetics of BI-706321 in healthy volunteers

New phase III trial studies capivasertib + paclitaxel for locally advanced or metastatic TNBC

TDP-43 screen identifies potential therapeutics for ALS and frontotemporal dementia

[18F]MNI-1126 detects synaptic density loss in Alzheimer's disease and Parkinson's disease patients

4D pharma initiates phase I/II study of MRx-4DP0004 for asthma

FDA accepts Celyad's IND application for autologous NKG2D-based CAR-T cell therapy CYAD-02

Intra-Cellular Therapies reports topline phase III data on lumateperone in bipolar depression

DMC recommends continuation of phase Ib study of AVB-500 in ovarian cancer

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