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BioWorld Science

April 16, 2021

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Homozygous stop-gain variant in SENP7 gene tied to congenital neutropenia

Researchers develop Phkg2-knockout mouse model of glycogen storage disease type 9

GLS-1027 studied in phase II to prevent severe pneumonitis caused by SARS-CoV-2

RAC1 gene mutations linked to prognosis in head and neck squamous cell carcinoma

GSK stops INDUCE-3 and INDUCE-4 studies evaluating feladilimab plus pembrolizumab

Phase III study of ciclesonide inhaler in COVID-19 does not meet statistical significance

First volunteer dosed in phase I study of COVID-19 candidate HLX-71

FDA lifts partial clinical hold on phase I study of SBP-101 in pancreatic cancer

INO-4800 provides broad cross-reactive immune responses against variant strains of SARS-CoV-2

Merck & Co. discontinues development of MK-7110 for COVID-19

First patient enrolled in phase I/II clinical program for QLS-101

Medshine Discovery patents CRAC blockers

Novartis divulges new EED and/or EZH2 inhibitors

Betta Pharmaceuticals identifies EGFR inhibitors

Nanjing TransThera Biosciences presents TAM family kinase inhibitors

New conjugated chimeric proteins presented by Orionis Biosciences

JNJ-74856665 mediates potent antileukemic activity and differentiation in preclinical models

Icatibant portion of I-SPY COVID trial ends after futility criterion met

Praxis initiates phase II/III trial of PRAX-114 for major depressive disorder

Enrollment opens in phase Ib study of RO-7122290 with cibisatamab in colorectal cancer

Discovery of allosteric MALT1 protease inhibitor JNJ-67856633 for cancer

Yale begins phase I study of BMS-984923 for Alzheimer's disease

Phase II trial of TQ-B3525 for advanced gynecological cancers begins enrollment

Aussie researchers show critical role of DC-SCRIPT in producing key dendritic immune cells

Ideaya reports preliminary phase I/II data on darovasertib in metastatic uveal melanoma

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