SAN FRANCISCO – Investors and entrepreneurs at the 12th Annual Cooley Healthtech Conference, undaunted by the trenchant challenges of integrating new technologies into a slow-changing U.S. health care system, said they're finding increasing purchase for businesses built on rich and growing datasets, ever-present connectivity and, in some cases, the irreplaceable magic of the human touch. With the pressures of macroeconomic uncertainties weighing less heavily on the sector than at last year's end, optimism abounded during two presentations assessing med tech's progress at the Wednesday event.