SAN FRANCISCO – Aspiring entrepreneurs looking to get the attention of big pharma got a healthy helping of practical pointers from gatekeepers at Abbvie Inc., Astrazeneca plc, Bayer AG, Medimmune Inc. and Merck & Co. Inc. during RESI's annual meeting. Panelists said that in recent years, their attentions have gravitated toward ever-earlier-stage opportunities but that best practices, such as not spamming their colleagues via email, remained unchanged.