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Home » AC Immune shares in free fall as Genentech halts crenezumab pivotal trials in Alzheimer's
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AC Immune shares in free fall as Genentech halts crenezumab pivotal trials in Alzheimer's

Jan. 31, 2019
By Cormac Sheridan
DUBLIN – "Unexpected, early and bad" was how Andrea Pfeifer, CEO of AC Immune SA, characterized the news that its partner, Genentech Inc., was terminating two phase III trials of anti-amyloid beta (a-beta) antibody crenezumab in Alzheimer's disease, following an interim analysis, which suggested that neither study would reach its primary endpoint. The Lausanne, Switzerland-based company's stock (NASDAQ:ACIU) was off by 37 percent during premarket trading Wednesday but went into free fall once the market opened. It ended the day at $3.65, a drop of 66 percent on its previous close.
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