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Home » Rhythm’s rare genetic obesity drug in first of two phase III studies
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Rhythm’s rare genetic obesity drug in first of two phase III studies

May 5, 2017
By Michael Fitzhugh
About three months after taking the wraps off a $41 million mezzanine financing, Rhythm Pharmaceuticals Inc. is kicking off a pivotal trial of its lead candidate, setmelanotide, for an ultra-rare genetic obesity disorder. The melanocortin-4 (MC4) receptor agonist will be tested in an open-label, single-arm phase III study evaluating its efficacy for the treatment of pro-opiomelanocortin (POMC) deficiency obesity, a condition estimated to affect between 100 and 500 patients in the U.S.
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