Medtronic (Minneapolis) reported the first patient was enrolled in its FIRE AND ICE clinical trial, which is a prospective, randomized, multinational head-to-head clinical trial comparing the long-term safety, effectiveness and ease-of-use of the Medtronic Arctic Front Cardiac CryoAblation System compared to the Biosense Webster (Diamond Bar, California) Carto System Guided Thermocool Catheter to treat patients with symptomatic paroxysmal atrial fibrillation.