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Home » Ionis shares sink as Roche quits dosing phase III HD drug following IDMC opinion
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Ionis shares sink as Roche quits dosing phase III HD drug following IDMC opinion

March 23, 2021
By Michael Fitzhugh
Shares of Ionis Pharmaceuticals Inc. (NASDAQ:IONS) fell 21.7% to $43.59 on March 23 after its longtime partner, Roche Holding AG, decided to stop dosing the antisense oligonucleotide tominersen in a global phase III manifest Huntington's disease (HD) study. Roche subsidiary Genentech Inc. said the move was based on an independent data monitoring committee's preplanned assessment of the drug's risk-benefit profile.
BioWorld Clinical Neurology/psychiatric

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