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Home » Italfarmaco unbowed after phase II muscular dystrophy miss for HDAC inhibitor
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Italfarmaco unbowed after phase II muscular dystrophy miss for HDAC inhibitor

June 28, 2021
By Michael Fitzhugh
Top-line data from a phase II trial of Italfarmaco SpA's givinostat in men with Becker muscular dystrophy found it failed to affect a significant change in total muscle fibrosis vs. placebo, the study's primary endpoint. But whether the outcome reflected a shortcoming of the drug or a function of the rare condition's clinical profile remained uncertain, with the company placing its bets on the latter.
BioWorld Clinical Musculoskeletal

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