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BioWorld - Wednesday, July 30, 2025
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Home » Blocking the KIR2DL5/PVR pathway boosts NK cell-based cancer immunotherapy
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Immuno-oncology

Blocking the KIR2DL5/PVR pathway boosts NK cell-based cancer immunotherapy

Dec. 7, 2022
NK cell-based cancer immunotherapy has emerged as an anticancer treatment approach and is currently being tested in clinical trials. KIR2DL5, a member of the human killer cell immunoglobulin-like receptor (KIR) family, has recently been identified as a binding partner for poliovirus receptor (PVR). However, the biology and therapeutic potential of the KIR2DL5/PVR pathway remain widely unexplored.
BioWorld Science Immunotherapy Cancer Immuno-oncology Monoclonal antibody

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