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Breaking News: Trump administration impacts continue to roil the life sciences sectorSee today's BioWorld Science
Home » CRISPR-associated nuclease combines specific recognition with wanton destruction
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Drug Design, Drug Delivery & Technologies

CRISPR-associated nuclease combines specific recognition with wanton destruction

Jan. 5, 2023
By Anette Breindl
CRISPR, or clustered regularly interspaced palindromic repeats, is transforming biomedical research, and making rapid inroads into the clinic, with its ability to easily target specific DNA and RNA sequences. CRISPR itself is made of RNA. It recognizes target sequences and delivers CRISPR-associated (Cas) proteins, nucleases that cut the target sequence. In two papers published online in Nature on Jan. 4, 2023, researchers have demonstrated that a recently discovered type of Cas protein, Cas12a2, can degrade double-stranded DNA when its associated CRISPR guide RNA recognizes its target sequence.
BioWorld Science Drug design, drug delivery and technologies RNA Diagnostics

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