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Breaking News: Trump administration impacts continue to roil the life sciences sectorSee today's BioWorld Science
Home » MCEMP1, a KIT receptor adaptor promoting mast cell proliferation in chronic airway inflammation
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Respiratory

MCEMP1, a KIT receptor adaptor promoting mast cell proliferation in chronic airway inflammation

April 28, 2023
Mast cell-expressed membrane protein 1 (MCEMP1) is a type II transmembrane protein predominantly expressed in myeloid lineage immune cells, including lung-resident mast cells and alveolar macrophages. MCEMP1 is a critical factor in allergic and inflammatory lung diseases, with higher expression levels correlating with increased disease severity. However, the molecular mechanisms underlying the role of MCEMP1 in the pathogenesis of lung inflammatory diseases remain unclear.
BioWorld Science Inflammatory Respiratory

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