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» Suzhou Kintor Pharmaceuticals describes new PROTACS to induce degradation of c-Myc, GSPT1, IKZF2 and CK1α
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Cancer
Suzhou Kintor Pharmaceuticals describes new PROTACS to induce degradation of c-Myc, GSPT1, IKZF2 and CK1α
July 24, 2023
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Suzhou Kintor Pharmaceuticals Inc. has identified proteolysis targeting chimera (PROTAC) compounds comprising cereblon (CRBN) binding moiety covalently linked to Myc proto-oncogene protein (c-Myc), eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1), zinc finger protein helios (IKZF2) and casein kinase 1 isoform α (CK1α).
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