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Home » Ripple EFX in FGF21s for NASH; 89bio hit by Akero’s phase IIb endpoint miss
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Ripple EFX in FGF21s for NASH; 89bio hit by Akero’s phase IIb endpoint miss

Oct. 10, 2023
By Randy Osborne
Hopes raised by the phase IIb Harmony study with FGF21 analogue efruxifermin (EFX) in pre-cirrhotic nonalcoholic steatohepatitis (NASH), which appeared in a scientific journal last week, were less than fulfilled as Akero Therapeutics Inc. rolled out disappointing 36-week results from another, same-stage trial called Symmetry in NASH patients with cirrhosis. The company is forging ahead with U.S. FDA talks to figure out how a phase III effort might be designed.
BioWorld Clinical Gastrointestinal

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