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» RMC-5127, a novel tri-complex inhibitor with efficacy in KRAS G12V-mutant tumor models
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Cancer
RMC-5127, a novel tri-complex inhibitor with efficacy in KRAS G12V-mutant tumor models
Oct. 23, 2023
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Researchers from Revolution Medicines Inc. presented the discovery and preclinical characterization of RMC-5127, a novel noncovalent, tri-complex inhibitor of GTPase KRAS (G12V mutant), or KRAS G12V(ON).
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AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics
Cancer