PYX-102 blocks KLRG1-cadherin interaction, activates CD8 T cells

Nov. 9, 2023

KLRG1 is expressed on a subset of T and NK cells, with KLRG1+CD8+ T cells having demonstrated strong antitumor cytotoxicity by releasing IFN-γ and TNF-α.

BioWorld Science Conferences Society for Immunotherapy of Cancer Cancer Immuno-oncology

Today's news in brief

BioWorld

BioWorld briefs for April 21, 2025.

Today's news in brief

BioWorld MedTech

BioWorld MedTech briefs for April 21, 2025.

Makary’s vision for slimmed-down US FDA somewhat reassuring

BioWorld

Nearly three weeks into the job, U.S. FDA Commissioner Marty Makary provided a comprehensive overview of his vision for the much-reduced agency, even as he’s...

Ouch! Tariffs hit med tech harder than expected

BioWorld MedTech

First quarter earnings reports from Johnson & Johnson and Abbott Laboratories provided some surprising insights into the likely hit med-tech companies will...

Dupixent bounces back in treating hives with FDA approval

BioWorld

The U.S. FDA issued a complete response letter in October 2023 for Dupixent (dupilumab) in treating chronic hives but has now approved the monoclonal antibody for...