Translational data on Regeneron’s leptin receptor agonist support further development

Nov. 24, 2023

REGN-4461 (mibavademab) is a monoclonal antibody targeting leptin receptor (LEP-R) under development by Regeneron Pharmaceuticals Inc. It acts as an allosteric agonist and does not compete with leptin binding to LEP-R.

BioWorld Science Endocrine/metabolic Monoclonal antibody

Today's news in brief

BioWorld

BioWorld briefs for April 22, 2025.

Today's news in brief

BioWorld MedTech

BioWorld MedTech briefs for April 22, 2025.

Makary’s vision for slimmed-down US FDA somewhat reassuring

BioWorld

Nearly three weeks into the job, U.S. FDA Commissioner Marty Makary provided a comprehensive overview of his vision for the much-reduced agency, even as he’s...

Dupixent bounces back in treating hives with FDA approval

BioWorld

The U.S. FDA issued a complete response letter in October 2023 for Dupixent (dupilumab) in treating chronic hives but has now approved the monoclonal antibody for...

Medtronic Simplera Sync and Minimed 780G pump system

Medtronic continues to close gap in diabetes tech

BioWorld MedTech

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