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Home » Arvinas, Pfizer broaden scope of ER-targeting therapy after impressive phase Ib breast cancer readout
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Arvinas, Pfizer broaden scope of ER-targeting therapy after impressive phase Ib breast cancer readout

Dec. 6, 2023
By Jennifer Boggs
While early stage and involving a relatively small patient population, the interim phase Ib readout from the combination cohort testing estrogen receptor (ER)-targeting candidate vepdegestrant in combination with CDK4/6 inhibitor Ibrance (palbociclib) in heavily pretreated patients with ER-positive/HER2-negative breast cancer was impressive enough to prompt partners Arvinas Inc. and Pfizer Inc. to expand development work on the program. The results also struck a chord on the Street, with shares of Arvinas (NASDAQ:ARVN) gaining 31% on the day.
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