Palisade Bio shows successful bioactivation of prodrug PALI-2108 into its active PDE4 inhibitor form

April 17, 2024

Palisade Bio Inc. has completed its analysis evaluating ex vivo bioactivation of PALI-2108, an orally administered, locally acting colon-specific phosphodiesterase-4 (PDE4) inhibitor prodrug in development for ulcerative colitis.

BioWorld Science Gastrointestinal

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BioWorld

BioWorld briefs for July 3, 2025.

Today's news in brief

BioWorld MedTech

BioWorld MedTech briefs for July 3, 2025.

AI-generated illustration of CAR T cells

Researchers arm CAR T cells to fight solid tumors

BioWorld

Aussie researchers have used CRISPR gene editing tools to “armor” chimeric antigen receptor (CAR) T cells to activate additional cancer-fighting proteins at the...

Bioversys, Shionogi in CHF529M lung infection collaboration

BioWorld Science

Antibiotics specialist Bioversys AG has sealed a potential CHF529 million (US$667.5 million) deal with Shionogi Co. Ltd., in which they will work together on...

Medtronic receives CE mark for its Vitalflow ECMO system

BioWorld MedTech

Medtronic plc received a CE mark for its Vitalflow extracorporeal membrane oxygenation (ECMO) system, which provides temporary support for the heart and lungs in...