PDE4 inhibitor ME-3183 shows promising preclinical efficacy in atopic dermatitis
Oct. 2, 2024
Phosphodiesterase 4 (PDE4) is an enzyme known to play a role in inflammatory responses, and it has been pinpointed as an interesting therapeutic target for diseases like atopic dermatitis (AD), but limited efficacy and side effects have prevented the approval of oral formulations.