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BioWorld - Thursday, November 14, 2024
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» Dyne Therapeutics’ DYNE-302 normalizes muscular pathology in preclinical FSHD
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Musculoskeletal
Dyne Therapeutics’ DYNE-302 normalizes muscular pathology in preclinical FSHD
Oct. 11, 2024
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Facioscapulohumeral muscular dystrophy (FSHD) is a severe muscle disorder caused by aberrant DUX4 mRNA expression in skeletal muscle. DUX4 activates downstream target transcriptome, known as D4T, leading to myofiber loss and muscle weakness.
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