LBL-042, a bispecific antibody targeting PD-1 and LILRB1/2 that can overcome resistance to PD-1 monotherapy
Nov. 20, 2024
A team from Nanjing Leads Biolabs Co. Ltd. presented the discovery and preclinical characterization of LBL-042, a novel bispecific antibody designed to simultaneously target PD-1 and LILRB1/2, with the aim of improving immune evasion of tumor microenvironment and potentially overcoming resistance to immuno-oncology therapy.