Proximity-activated antibody-cytokine fusion protein reinvigorates tumor-specific PD-1-expressing T cells
Nov. 29, 2024
Researchers from Anaveon AG and affiliated organizations presented the discovery and preclinical characterization of ANV-700, a novel proximity-activated cytokine (PAC) compound designed to selectively deliver IL-21 to PD-1-expressing cells for the treatment of cancer.