A disintegrin and metalloprotease domain-like protein decysin-1 (ADAMDEC1) is a multifunctional transmembrane glycoprotein that has been shown to promote metastasis and development of various tumor types by degrading the extracellular matrix. Scientists at Nankai University and affiliated organizations aimed to assess the regulatory mechanisms of ADAMDEC1 in the highly aggressive cancer cholangiocarcinoma (CCA).