Neuropeptide Y identified as driver of pancreatic cancer metastasis
March 18, 2025
Pancreatic cancer is still among the most lethal cancers, with >45% of patients presenting distant metastasis at diagnosis, and with a 5-year survival rate of 13%. Known for its role in appetite and energy homeostasis, neuropeptide Y (NPY) is the most common neuropeptide in the central and peripheral nervous system, acting through its receptor NPY1R, among others.