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Home » Ionis Pharmaceuticals Inc.

Articles Tagged with ''Ionis Pharmaceuticals Inc.''

R&D money

Biopharmas increase their R&D spending in 2019, analysis finds

March 10, 2020
By Peter Winter
According to an analysis conducted by BioWorld of the fourth-quarter and year-end 2019 financial reports filed by the top 100 public biopharmaceutical companies ranked by market cap, and excluding big pharma companies, the amount that was invested in research and development (R&D) during the year increased 35% compared to the same period in 2018.
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Brain-DNA illustration

Trinucleotide expansions are too much of a good thing

Feb. 26, 2020
By Anette Breindl
Everything’s good for something. Including, it turns out, 5’ untranslated trinucleotide repeats. In the Feb. 17, 2020, issue of Nature Neuroscience, researchers have demonstrated a role for such repeats in controlling protein levels of fragile X mental retardation protein (FMRP).
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Aro hits mark via top-Tyr antisense deal; Ionis comes ‘nocking’ with as much as $1.4B

Jan. 9, 2020
By Randy Osborne
Philadelphia-based Aro Biotherapeutics Co. CEO Sue Dillon told BioWorld her firm has “incoming interest from other companies to apply Centyrins to other kinds of drug conjugates,” which could mean more deals with the platform like the one sealed with Ionis Pharmaceuticals Inc.
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Connecting puzzle pieces

Empirico scores $660M deal with Ionis and lands series A-2 financing

Jan. 9, 2020
By Lee Landenberger
It’s a big day for privately held Empirico Inc. as it embarks on a massive combo pharma deal with Ionis Pharmaceuticals Inc. while racking up a $17 million series A-2 financing.
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Akcea and Pfizer sign $250M up-front deal

Oct. 8, 2019
By Lee Landenberger
Akcea Therapeutics Inc., a majority owned affiliate of Ionis Pharmaceuticals Inc., and Pfizer Inc. signed an exclusive, worldwide licensing deal for AKCEA-ANGPTL-3-LRx, which is being developed to treat cardiovascular and metabolic diseases. The deal follows a period during which Akcea's stock (NASDAQ:AKCA) has sagged prior to rising Monday and big changes in the company's C-suite.
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