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Home » Staphylococcus aureus

Articles Tagged with ''Staphylococcus aureus''

Staphylococcus aureus

Analysts positive, market not so much, on Aridis phase III MAb data for S. aureus VAP

Jan. 26, 2023
By Karen Carey
Low enrollment in a phase III trial and a missed primary endpoint sent Aridis Pharmaceuticals Inc.’s shares tumbling by 35% on Jan. 26, although the company’s AR-301 (tosatoxumab) showed superior efficacy over the control group in Staphylococcus aureus ventilator-associated pneumonia (VAP) patients.
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Bacterial colonies in petri dishes
Infection

Discovery of novel multitargeting antibacterial agents

Jan. 12, 2023
Scientists from Southwest University and...
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Deal illustration

Bio-Rad strikes $170M deal for Curiosity Diagnostics

Aug. 4, 2022
By Catherine Longworth
Bio-Rad Laboratories Inc. signed a $170 million deal to acquire all the outstanding shares of molecular diagnostics subsidiary Curiosity Diagnostics SpZoo from Scope Fluidics SA. The deal consists of approximately $100 million in cash and up to $70 million in future milestone payments. The pre-commercial platform company is the developer of a CE-marked 15-minute point-of-care (POC) rapid PCR system which tests for SARS-CoV-2 virus and methicillin-resistant or-sensitive Staphylococcus aureus bacteria (MRSA/MSSA).
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Stop in the name of futility: Contrafect halts enrollment in phase III study

July 14, 2022
By Lee Landenberger
The data safety monitoring board overseeing Contrafect Corp.’s phase III study of exebacase, a hydrolase stimulator for treating Staphylococcus aureus bacteremia, recommended the study be stopped. In an interim analysis, the board said the conditional power of the study was below the prespecified threshold for futility.
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Viruses

Pandemic’s unwanted gift opens opportunities for AMR vaccines

July 13, 2022
By Mari Serebrov
COVID-19 is the unwanted gift that keeps on giving. The U.S. CDC unwrapped one of those “presents” in a July 12 report that showed the threat of antimicrobial-resistant (AMR) infections has worsened — with resistant hospital-onset infections and deaths in the U.S. each increasing at least 15% during the first year of the pandemic.
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Staphylococcus aureus

MRSA superbug has prickly origins

Jan. 7, 2022
By Nuala Moran
The accepted wisdom that resistance to antibiotics is a modern phenomenon driven by their overuse is called into question by new research showing the genes that give methicillin-resistant Staphylococcus aureus (MRSA) its superbug status existed in nature long before antibiotics were first deployed in the clinic.
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Large intestine illustration

Probiotic strategy prevents Enterococcus escape from the gut

Nov. 24, 2021
By Anette Breindl
“I was not always someone who would have advertised probiotics,” Michael Otto told BioWorld. And it’s easy to see why. At this point, probiotics are more often dubious wellness offerings than evidence-based therapeutics. Part of the issue is that the mechanisms by which probiotics are supposed to exert their effects are mostly vague. Molecular mechanisms that could account for claimed health benefits are few and far between. But Otto, who is chief of the pathogen molecular genetics section at the National Institutes of Allergy and Infectious Disease, and his colleagues have identified one such molecular mechanism.
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Drug capsules in petri dish

Micurx wins China approval for antibacterial contezolid

June 8, 2021
By Elise Mak
Micurx Pharmaceuticals Inc. has won marketing approval from China's NMPA for its lead antibacterial, contezolid, for treating adults with complicated skin and soft tissue infection (cSSTI), marking the first NDA for the Shanghai drugmaker. Set to be marketed as Youxitai in China, Micurx discovered the new-generation oral oxazolidinone antibiotic, developing it over 12 years. It’s designed to treat multidrug-resistant gram-positive bacteria such as methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococci.
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Botanix’s cannabidiol eradicates Staphylococcus aureus bacteria in phase IIa nasal colonization study

Feb. 9, 2021
By Tamra Sami
PERTH, Australia – Synthetic cannabinoid company Botanix Pharmaceuticals Ltd. announced top-line data from a phase IIa study showing that two different formulations of BTX-1801, a synthetic cannabidiol (CBD), eradicated Staphylococcus aureus (staph) in the nose, meeting study endpoints for safety and efficacy. 
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Botanix’s cannabidiol eradicates Staphylococcus aureus bacteria in phase IIa nasal colonization study

Feb. 4, 2021
By Tamra Sami
PERTH, Australia – Synthetic cannabinoid company Botanix Pharmaceuticals Ltd. announced top-line data from a phase IIa study showing that two different formulations of BTX-1801, a synthetic cannabidiol, eradicated Staphylococcus aureus (staph) in the nose, meeting study endpoints for safety and efficacy. 
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