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Home » chemotherapy

Articles Tagged with ''chemotherapy''

Conncons smart infusion
Patents

Conncons smart medical infusion systems monitor drug reservoirs

Nov. 1, 2023
By Simon Kerton
Conncons GmbH filed for patent protection of its networked medical infusion systems. The connecting components of their infusion systems house sensors that can detect data associated with medications in drug reservoirs.
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electroporation system
Patents

Researchers develop electroporation system to induce lysis of circulating tumor cells during hemodialysis

Oct. 2, 2023
By Simon Kerton
U.S. researchers reported seeking patent protection for methods to neutralize circulating tumor cells (CTCs) during hemodialysis to prevent cancer metastasis and reduce cancer-related deaths.
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Endometrial/uterine cancer illustration

FDA approves Anaptysbio’s GSK-partnered biologic Jemperli in combination with chemo

Aug. 1, 2023
By Caroline Richards
About two months ahead of the planned PDUFA date, the U.S. FDA has granted expanded approval of PD-1 antibody Jemperli (dostarlimab) from partners Anaptysbio Inc. and GSK plc for use in combination with standard-of-care chemotherapy. GSK said the drug would be the only frontline immuno-oncology treatment for endometrial cancer available in combination with carboplatin and paclitaxel. The supporting supplemental BLA for the expanded indication previously received priority review.
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Pancreas
Cancer

NIH grant supports partnership to study TGX-1214 with immune checkpoint inhibition for PDAC

Feb. 10, 2023
UC Davis Comprehensive Cancer Center is partnering with Targagenix Inc. and Northeastern University to study pancreatic ductal adenocarcinoma (PDAC). The partnership will receive nearly US$3 million over 5 years through funding from the National Institutes of Health (NIH).
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CV6 Therapeutics gets ready to ‘dUMP’ cancer with dUTPase inhibitor

Nov. 2, 2022
By Cormac Sheridan
CV6 Therapeutics Ltd. raised $9.2 million in grant and equity funding to move a first-in-class inhibitor of deoxyuridine 5’-triphosphate nucleotidohydrolase (dUTPase) into a phase Ia trial in cancer. The compound, CV6-168, will from the outset be administered in combination with fluorouracil, a mainstay of chemotherapy for the past 60 years.
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RNA

RNA-binding protein helps colon cancer cells persist

July 5, 2022
By Anette Breindl
Researchers have identified an RNA-binding protein that played a role in colon cancer relapse, offering new insights into how cells persist in the presence of chemotherapy.
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Health professional pointing stethoscope at Clinical Trial words, icons

CRLs make week's start rough start for four companies

May 3, 2022
By Lee Landenberger
A quartet of companies on May 2 announced three complete response letters (CRLs) that left them scrambling to get back on the path to approval. Hutchmed Ltd.'s surufatinib met with word from the U.S. FDA that two positive phase III studies in China and a bridging study in the U.S. would not support approval of the drug for pancreatic and extra-pancreatic neuroendocrine tumors. A multi-regional clinical trial in the U.S. is needed, the regulator said, brushing aside China-only studies when seeking a U.S. approval.
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CRLs make week's start rough start for four companies

May 2, 2022
By Lee Landenberger
A quartet of companies on May 2 announced three complete response letters (CRLs) that left them scrambling to get back on the path to approval. Hutchmed Ltd.'s surufatinib met with word from the U.S. FDA that two positive phase III studies in China and a bridging study in the U.S. would not support approval of the drug for pancreatic and extra-pancreatic neuroendocrine tumors. A multi-regional clinical trial in the U.S. is needed, the regulator said, brushing aside China-only studies when seeking a U.S. approval.
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Daiichi Sankyo releases top-line phase III data for FLT3 inhibitor quizartinib

Nov. 23, 2021
By Gina Lee
Top-line results of Daiichi Sankyo Co. Ltd.’s phase III Quantum-First study, testing the addition of quizartinib to chemotherapy vs. chemotherapy alone for adults with newly diagnosed FLT3-ITD positive acute myeloid leukemia (AML), found the combination therapy provided a “statistically significant and clinically meaningful improvement” in overall survival vs. standard treatment alone, meeting the trial’s primary endpoint, Ken Takeshita, global head of R&D at Daiichi Sankyo, told BioWorld.
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Red dart in center of red target

FDA clearance for Renovocath delivery system sends Renovorx’s stock higher

Sep. 10, 2021
By Catherine Longworth
The share price of Renovorx Inc. has spiked following FDA clearance for its Renovocath delivery system. Since the company announced the clearance, its stock (NASDAQ:RNXT) has climbed by more than 13%. Last month the company completed an IPO for approximately $16.6 million, issuing shares at $9-$11.
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