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Home » Black Diamond Therapeutics Inc.

Articles Tagged with ''Black Diamond Therapeutics Inc.''

Cancer

Black Diamond Therapeutics discloses EGFR inhibitors for cancer

July 16, 2025
A Black Diamond Therapeutics Inc. patent describes new alkyne-substituted quinazoline derivatives acting as EGFR (HER1; erbB1) inhibitors particularly, EGFR mutant inhibitors, potentially useful for the treatment of cancer.
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Black Diamond lands $780M Servier deal for RAS/RAF candidate

March 19, 2025
By Jennifer Boggs
Black Diamond Therapeutics Inc. is getting $70 million up front and could earn up to $710 million in milestone payments in a deal with Servier for phase I-stage BDTX-4933, a small-molecule candidate targeting both RAS mutations and RAF alternations for treating solid tumors, including non-small-cell lung cancer.
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Cancer

Black Diamond Therapeutics patents new PI3Kα inhibitors

Feb. 22, 2024
Quinoxaline derivatives acting as phosphatidylinositol 3-kinase α (PI3Kα) (H1047R mutant) and/or (E545K mutant) inhibitors have been described in a Black Diamond Therapeutics Inc. patent.
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No longer in the rough: Black Diamond posts strong phase I NSCLC data

June 27, 2023
By Lee Landenberger
The dose-escalation portion of Black Diamond Therapeutics Inc.’s phase I study of BDTX-1535 for treating non-small-cell lung cancer (NSCLC) produced strong data that moved the market in a big way.
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Cancer

Black Diamond Therapeutics divulges new B-Raf mutant inhibitors for cancer

April 4, 2023
Black Diamond Therapeutics Inc. has synthesized quinoline derivatives acting as Raf kinase B (B-Raf) mutant inhibitors reported to be useful for the treatment of cancer.
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Lab glassware and scientist
Cancer

Preclinical characterization of CNS-penetrant BRAF class I/II/III mutation inhibitor BDTX-4933

Nov. 14, 2022
Researchers from Black Diamond Therapeutics Inc. presented the discovery and preclinical characterization of a novel brain-penetrant BRAF class I/II/III mutation inhibitor, BDTX-4933.
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Cancer

Black Diamond Therapeutics presents FGFR2 and/or FGFR3 inhibitors

Sep. 1, 2022
Black Diamond Therapeutics Inc. has patented quinoxaline derivatives acting as fibroblast growth factor receptor 2 (FGFR2) and/or FGFR3 inhibitors reported to be useful for the treatment of cancer.
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Cancer cells

Black Diamond in the rough as many-faceted ASCO abstracts drop

May 20, 2021
By Randy Osborne
CEO David Epstein said Black Diamond Therapeutics Inc. was “delighted” with phase I data testing BDTX-189 in advanced solid tumors harboring EGFR or HER2 alterations, but Wall Street seemed less so. Shares (NASDAQ:BDTX) closed at $13.93, down $8.30, or 37%.
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IPO, coins, upward arrow
Open window

Challenging markets do not deter flow of biopharma IPOs

May 5, 2020
By Peter Winter

Although, the appetite for biopharma IPOs in the U.S. slowed during the meltdown of the financial markets in March, the flow of new offerings has been steady this year, according to BioWorld, with 11 companies graduating to the public stage and listing on U.S. exchanges by the end of April, collectively raising $1.774 billion along the way. This amount is 9.5% higher than the $1.62 billion raised from 15 U.S. biopharma IPOs completed in the same period last year.


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Dollar sign thermometer
Great expectations

Lukewarm start to year weighs heavily on sector’s performance

Feb. 3, 2020
By Peter Winter
Biotech investors had every reason to feel bullish heading into the new decade. The sector had turned around in 2019 and was riding a wave of a very strong fourth-quarter performance, with the BioWorld Biopharmaceutical Index closing up 14% for the year after being underwater from April through to September. Unfortunately, those great expectations were quickly erased during J.P. Morgan Healthcare conference week (Jan. 10 – Jan. 17), which turned out to be a very low-key affair absent of any blockbuster M&A revelations. As a result, confidence has now given way to concerns about the prospects for biopharmaceutical companies going forward, particularly as unfavorable political rhetoric on drug pricing will certainly be dialed up during this election year.
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