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Home » IL-2

Articles Tagged with ''IL-2''

Mouse model of ovarian cancer.
Immuno-oncology

Genuv announces bifunctional fusion protein GNUV-205 for solid tumors

Oct. 13, 2022
Genuv Inc. has announced a new drug candidate...
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Scientist, microscope and dropper
Inflammatory

Delivery of engineered Tregs with tunable IL-2 signaling support enhances Treg potency and survival

Sep. 15, 2022
Gentibio Inc. has announced preclinical data relating to the company's platform technology, demonstrating technical progress to engineer regulatory T cells (Tregs) for the prevention and treatment of autoimmune diseases.
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Hands holding gears

Bonum to continue Good work after $250M cash acquisition deal with Roche

Sep. 7, 2022
By Jennifer Boggs
For privately held Good Therapeutics Inc., founded in 2016 with a platform technology for developing context-dependent therapeutics, the plan had always been to seek a buyer for the first asset to emerge. One came along a little earlier than expected, as Roche Holding AG entered a merger agreement for Good, picking up preclinical-stage PD-1-regulated IL-2 program, in exchange for an up-front cash payment of $250 million.
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Cancer cell destruction by nanoparticles

Engineered retinal cells stare daggers at peritoneal tumors

March 4, 2022
By Anette Breindl
By using engineered retinal pigment epithelial cells to deliver IL-2 into the tumor microenvironment, investigators at Rice University eradicated ovarian and colorectal tumors in mouse models, and elicited T-cell responses after implantation in primates.
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Anaveon closes $120M B round to accelerate IL-2 agonist development

Dec. 16, 2021
By Cormac Sheridan
DUBLIN – Anaveon AG raised CHF110 million (US$119.5 million) in a series B round to accelerate development of its interleukin-2 (IL-2) agonist ANV-419, which is currently undergoing a phase I/II trial. “We are putting our compound into multiple clinical trials and multiple indications in parallel,” CEO and co-founder Andreas Katopodis told BioWorld.
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Craig Gibbs, CEO, Asher Biotherapeutics

Asher Bio closes $108M series B round to move IL-2 program to the clinic in 2022

Sep. 1, 2021
By Cormac Sheridan
Less than six months after closing a $55 million series A round, Asher Biotherapeutics Inc. has added another $108 million in a series B round to accelerate development of its early stage pipeline of targeted cytokine-based immunotherapies for cancer, autoimmune disease and infection.
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Gold dollar sign

Space burgeons, investors splurgin’ as Wall Street mulls likely cytokine winners

June 14, 2021
By Randy Osborne
The hefty $107.5 million series B financing disclosed June 10 by Synthekine Inc. underscored Wall Street’s interest in engineered cytokines, where an army of companies is developing prospects at varying stages – including Bright Peak Therapeutics Inc., which pulled down a series B in almost exactly the same amount as Synthekine, and on the same day.
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Bright Peak closes $107M series B round as engineered cytokine space heats up

June 10, 2021
By Cormac Sheridan
Bright Peak Therapeutics Inc. closed a $107 million series B round to progress a pipeline of engineered cytokines, which are produced using a chemical synthesis method instead of classical recombinant protein production approaches.
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T cells

Asher Bio closes $55M series A round for targeted IL-2 drugs

March 23, 2021
By Cormac Sheridan
Asher Biotherapeutics Inc. raised $55 million in a series A financing round to take forward a series of engineered cytokines designed to selectively activate T cells or other immune effector cells, in order to eliminate both the toxicities and the loss of efficacy that can result from indiscriminate activation.
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Gold wireframe handshake

Rapid returns for shareholders as Pandion agrees to $1.85B Merck buyout

Feb. 25, 2021
By Cormac Sheridan
Merck & Co. Inc. is paying $1.85 billion, or $60 per share, to acquire Pandion Therapeutics Inc. on the back of early stage data in human volunteers for its lead program, PT-101, an engineered interleukin-2 mutein fused to an Fc backbone, which is designed to stimulate targeted expansion of regulatory T cells for use in autoimmune disease indications.
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