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Home » Seagen Inc.

Articles Tagged with ''Seagen Inc.''

T cells

Lava soars on $700M Seagen deal for EGFR Gammabody candidate

Sep. 26, 2022
By Jennifer Boggs
Shares of Lava Therapeutics NV rocketed by more than 90% Sept. 26 as the company disclosed a licensing deal with Seagen Inc. to develop and commercialize preclinical-stage EGFR-targeting bispecific candidate LAVA-1223, which comes with $50 million in up-front funding and up to a potential $650 million in milestones. It also adds further validation for harnessing gamma-delta T cells to treat cancer, an approach that is growing increasingly popular.
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Cancer

US researchers disclose new TLR7 or TLR8 agonists

Sep. 2, 2022
Seagen Inc. and University of Minnesota have synthesized compounds and their antibody-drug conjugates (ADCs) comprising humanized monoclonal antibody (MAb) bound to Toll-like receptor 7 (TLR7) or TLR8 agonists through linker reported to be useful for the treatment of cancer.
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Aiming to build a better ADC, Emergence raises $98M in series A

Dec. 7, 2021
By Nuala Moran
LONDON – Europe’s latest antibody-drug conjugate (ADC) specialist, Emergence Therapeutics AG, will be going head to head with pioneer Seagen Inc.’s approved ADC, Padcev, after raising €87 million (US$97.9 million) in a series A round.
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Padcev vial

Astellas and Seagen win Japanese approval for Padcev in advanced urothelial cancer

Sep. 28, 2021
By David Ho
Astellas Pharma Inc. and Seagen Inc. received approval through a priority review from Japan's Ministry of Health, Labour and Welfare for Padcev (enfortumab vedotin) to treat radically unresectable urothelial carcinoma that has progressed after chemotherapy. The green light for the antibody-drug conjugate is based on the global phase III EV-301 clinical trial, which included sites in Japan.
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FDA approved metal stamp

Genmab-Seagen win FDA approval for cervical cancer therapy Tivdak

Sep. 21, 2021
By Michael Fitzhugh
Little more than six months after filing a BLA for the antibody-drug conjugate (ADC) tisotumab vedotin in recurrent or metastatic cervical cancer, Seagen Inc. and Genmab A/S have secured an accelerated approval for the medicine. The green light for the co-developed product marks Seagen's third approved ADC and Genmab's first marketed therapy, though another medicine based on its Duobody technology platform recently won approval, too. The new cervical cancer drug, to be marketed as Tivdak, was approved for the treatment of adults experiencing disease progression on or after chemotherapy.
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Disitamab vedotin

In a $2.6B deal, Seagen and Remegen target HER2 with an ADC

Aug. 10, 2021
By Lee Landenberger
Seagen Inc. and Remegen Co. Ltd. will collaborate to exclusively develop and commercialize disitamab vedotin, a humanized antibody-drug conjugate (ADC) targeting HER2, giving Remegen the chance to earn up to $2.4 billion in total milestone payments.
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Disitamab vedotin

In a $2.6B deal, Seagen and Remegen target HER2 with an ADC

Aug. 9, 2021
By Lee Landenberger
Seagen Inc. and Remegen Co. Ltd. will collaborate to exclusively develop and commercialize disitamab vedotin, a humanized antibody-drug conjugate (ADC) targeting HER2, giving Remegen the chance to earn up to $2.4 billion in total milestone payments.
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Drug pricing illustration

Pandemic puts pressure on drug sales

Jan. 19, 2021
By Brian Orelli
The 39th Annual J.P. Morgan Healthcare Conference was sans Celgene Corp.'s annual tradition of kicking off the conference with preliminary revenue and earnings from the previous year, but plenty of other companies stepped up and offered preliminary results of their own. Unfortunately, some companies continued to face headwinds selling drugs during the pandemic as patients avoided their doctors' offices.
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Coronavirus and stock charts

Biopharma companies hit a rough patch in October

Nov. 2, 2020
By Peter Winter
The dramatic increase in COVID-19 infections in Europe and the U.S., combined with information overload surrounding the lead up to the Nov. 3 contentious U.S. presidential election, was more than enough to send investors to the sidelines in October.
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Nectin-4 case built for two? Bicycle puts pedal to the mettle

Oct. 19, 2020
By Randy Osborne
Cambridge, U.K.-based Bicycle Therapeutics plc’s phase I dosing about a month ago of its first patient with nectin-4-targeting BT-8009 put the company on the road to hoped-for success by pursuing the same mechanism of action as Padcev (enfortumab vedotin-ejfv), the antibody-drug conjugate (ADC) from Astellas Pharma Inc. and Seagen Inc.
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