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BioWorld - Monday, August 4, 2025
Home » acute ischemic stroke

Articles Tagged with ''acute ischemic stroke''

Pregnancy

Diamedica’s DM-199 shows promise for serious pregnancy disorder

July 18, 2025
By Karen Carey
No Comments
After expanding development of DM-199 (rinvecalinase alfa) into preeclampsia last year, Diamedica Inc. rolled out early phase II results showing the recombinant form of human tissue kallikrein-1 reduced the mother’s blood pressure, did not cross the placental barrier, and potentially improves blood flow to the fetus.
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Cross-section of brain
Neurology/psychiatric

Blocking GAPDH aggregation to mitigate stroke injury

May 8, 2025
No Comments
Stroke accounts for nearly 12% of all deaths worldwide, making it the second leading cause of death. In acute ischemic stroke, the ischemia and subsequent return of blood flow create oxidative and nitrosative stress that can overwhelm neurons and disable important circuitry.
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Sanbexin sublingual tablets

NMPA clears drugs from Innovent/Hutchmed, Hengrui, Henlius, Luye

Dec. 10, 2024
By Marian (YoonJee) Chu
China’s National Medical Products Administration (NMPA) granted new approvals to several Chinese biopharmaceuticals this week, including expanding indications of four different cancer drugs and clearing one sublingual tablet for stroke.
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Sanbexin sublingual tablets

NMPA clears drugs from Innovent/Hutchmed, Hengrui, Henlius, Luye

Dec. 5, 2024
By Marian (YoonJee) Chu
China’s National Medical Products Administration (NMPA) granted new approvals to several Chinese biopharmaceuticals this week, including expanding indications of four different cancer drugs and clearing one sublingual tablet for stroke.
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Nelonemdaz

Phase III data positive for GNT's neuroprotective stroke drug

Feb. 20, 2024
By Marian (YoonJee) Chu
South Korean biopharmaceutical firm GNT Pharma Co. Ltd. on Feb. 13 reported positive findings from a domestic phase III trial of its neuroprotectant therapy, nelonemdaz (NEU-2000), for patients with acute ischemic stroke.
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Nelonemdaz

Phase III data positive for GNT's neuroprotective stroke drug

Feb. 14, 2024
By Marian (YoonJee) Chu
South Korean biopharmaceutical firm GNT Pharma Co. Ltd. on Feb. 13 reported positive findings from a domestic phase III trial of its neuroprotectant therapy, nelonemdaz (NEU-2000), for patients with acute ischemic stroke.
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Ischemic stroke
Neurology/Psychiatric

Aruna’s AB-126 cleared to enter clinic for acute ischemic stroke

Jan. 17, 2024
Aruna Bio Inc. has gained FDA clearance for its IND application for AB-126, enabling initiation of a phase Ib/IIa trial in acute ischemic stroke.
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China’s Ji Xing signs flurry of Asian deals to advance cardiovascular pipeline and global ambitions

Jan. 16, 2024
By Tamra Sami
Shanghai-based Ji Xing Pharmaceuticals has signed a number of licensing deals over the last week for China rights to cardiovascular drugs to advance its pipeline and its global ambitions, partnering most recently with Tokyo-based TMS Co. Ltd. after the Chinese company acquired global rights for TMS-007 (also known as BIIB-131) from Biogen Inc.
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China’s Ji Xing signs flurry of Asian deals to advance cardiovascular pipeline and global ambitions

Jan. 12, 2024
By Tamra Sami
Shanghai-based Ji Xing Pharmaceuticals has signed a number of licensing deals over the last week for China rights to cardiovascular drugs to advance its pipeline and its global ambitions, partnering most recently with Tokyo-based TMS Co. Ltd. after the Chinese company acquired global rights for TMS-007 (also known as BIIB-131) from Biogen Inc.
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Sensome Clotild graphic

Sensome forges partnership with Asahi Intecc for next-generation AI-assisted guidewire

July 3, 2023
By Bernard Banga
Sensome SAS reported a partnership with Asahi Intecc Co. Ltd. to develop the next generation Clotild smart guidewire. Asahi Intecc is taking on the manufacturing role for Sensome’s smart guidewire designed for the treatment of acute ischemic stroke.
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