It has been more than 200 years since British doctor James Parkinson first identified the symptoms of a condition that he termed shaking palsy; unfortunately, there is still no cure to the disease that carries his name.

In order to redirect health care resources and protect patients during the COVID-19 pandemic, many drug companies have paused enrollment in some or all of their ongoing clinical trials. But patients still in the studies need to be followed for safety and efficacy, creating challenges for the industry.

Therapeutic area data reported by biopharma companies on phase I trials in March 2020, including: Actinium, Allergan, Aptevo, Aravive, Arrowhead, Artugen, Asana, Biocryst, Biomx, Bolt, Cabaletta, CNS, Cohbar, Compugen, Cyclo, Cytodyn, Dare, Debiopharm, Decibel, Discgenics, Dynacure, Enlivex, Eton, Evelo, Faron, Fulcrum, Gemoab, Genetx, Gilead Sciences, GT, Imcheck, Immutep, Inflarx, Inflazome, Inmed, Innate, Kancera, Kiniksa, Lattice, Matinas, Medivir, Mersana, Mina, Moderna, Novartis, Oncolytics, Oncopeptides, Oncternal, Orchard, Pliant, Prevail, Psioxus, Redhill, Seelos, Synlogic, Targovax, Terns, Tolero, Uniqure.

Therapeutic area data reported by biopharma companies on phase II trials in March 2020, including: Acceleron, Akero, Albireo, Algernon, Allakos, Axsome, Can-Fite, Cellphire, Chugai, Cortexyme, Cytodyn, Delmar, Diffusion, Engage, Genfit, Hansa, Horizon, Ideaya, Immutep, Innovent, Inovio, Irlab, ISA, Leading, Matinas, Mediwound, Moderna, Nantkwest, Neuraly, Obseva, Oncolys, Oncoquest, Opthea, Orchard, Orphomed, Orthotrophix, Ovid, Palvella, Phasebio, Proqr, Qurient, Redhill, Regeneron, Revive, Sanofi, Santen, Seres, Synlogic, Tenax, Theralase, Theranexus, Tracon, Uniqure, Vaccitech, Vivoryon, Xenon, Zealand.

During the first quarter of 2020, a total of 153 financings brought $13.2 billion into the med-tech industry, representing a 20% drop from the first quarter of 2019, but still significantly above all of the other quarters since 2017. The number of private financings appears to be climbing in comparison with recent years, and some large notes offerings have placed private raises of public companies on top. In contrast, IPOs and follow-on offerings are way down from previous quarters.