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Home » Topics » Science » Immunotherapy

Immunotherapy
Immunotherapy RSS Feed RSS

Valo raises €19M for immunotherapy work

March 11, 2025
By Nuala Moran
Finnish cancer immunotherapy specialist Valo Therapeutics Oy has raised €19 million (US$20.7 million) in a round that attracted Italian and Australian investors, and funding the company to the completion of the ongoing phase Ib trial of its lead program in the treatment of solid tumors.
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Hand holding dollar sign
Cancer

LTZ completes series A of more than $20M

Aug. 1, 2024
LTZ Therapeutics Inc. has completed a series A financing of more than $20 million to advance the development of its myeloid engager pipeline to treat cancer and autoimmune diseases. The closing of this round brings LTZ’s total funding to about $50 million.
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Cross section illustration of HIV virus parts
HIV/AIDS

IAS 2024: Seventh HIV cure reported, but broad reach will take other approaches

July 22, 2024
By Anette Breindl
The 2024 meeting of the International AIDS Society (IAS), which is being held in Munich this week, began with the announcement of another curative bone marrow transplant. The new case brings the total number of patients cured of HIV via a bone marrow transplant up to 7 since “Berlin patient” Timothy Ray Brown became the first such person in 2007.
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Vaccine vial and syringe
Immuno-oncology

Cancervax announces discovery of bispecific antibody vaccine for Ewing sarcoma

April 16, 2024
A research team at University of California, Los Angeles (UCLA), funded by Cancervax Inc., has created a promising new bispecific antibody vaccine for treating recurrent Ewing sarcoma.
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Immune checkpoint inhibitors illustration of PD-1, CTLA-4 and PD-L1.
Immuno-oncology

New funding at Conformation-X supports pipeline of immune checkpoint inhibitors

April 4, 2024
Conformation-X Therapeutics LLC has closed an oversubscribed funding tranche of $3.65 million to support the company’s development of a pipeline of immunotherapies that activate both the innate and adaptive arms of the immune system.
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Cells, DNA illustration
Immuno-oncology

Epitope editing in hematopoietic cells provides CAR T immunotherapy against all types of blood cancer

Sep. 22, 2023
A new method of CAR T-cell immunotherapy developed by researchers at the University of Pennsylvania Perelman School of Medicine could serve as a treatment for most blood cancers. Until now, CAR T-based immunotherapy for hematological malignancies has targeted the antigens CD19 for B cells, CD7 for T cells, BCMA for myeloma, and CD33 for AML.
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Illustration of cancer cells and immunotherapy treatment
Immuno-oncology

Hanchorbio and Henlius collaborate to develop novel cancer immunotherapies

Aug. 29, 2023
Hanchorbio Inc. and Shanghai Henlius Biotech Inc. have entered into a strategic framework agreement for collaboration to combine Hanchorbio’s protein engineering expertise and proprietary Fc-based designer biologics (FBDB) technology platform with Henlius’ integrated product development and commercialization capabilities.
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Immuno-oncology

Killer T cells go after MHC-I-deficient tumors through NKG2D receptor

Aug. 24, 2023
Adaptative immune response mediated by NKG2D receptor and its ligand NKG2DL could be the clue for CD8-expressing “killer” T cells to kill tumors lacking the major histocompatibility complex (MHC) class I, according to a group of researchers at Duke University.
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Antibodies attacking cancer cell
Immuno-oncology

FDA clears Georgiamune’s IND application for GIM-122

Aug. 10, 2023
Georgiamune Inc. announced that the FDA cleared its IND application for GIM-122, a first-in-class dual-functioning monoclonal antibody designed to target a highly novel mechanism to overcome immunotherapy resistance.
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Cartography immunotherapy target illustratio
Immuno-oncology

Precision target discovery at forefront for immunotherapy startup Cartography

July 11, 2023
By Caroline Richards
Most drug developers working in the immunotherapy space focus on existing therapeutic targets when developing cancer drugs, optimizing ways of drugging them via engineering modalities such as CAR T-cell approaches, CRISPR editing or antibody-drug conjugates that deliver toxic payloads. The angle of one company – Cartography Biosciences – is the opposite to this. Its modus operandi is to pinpoint the immunological targets first, leveraging tools that already exist, before building therapies around them.
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