Updated results from a phase II test of Viking Therapeutics Inc.'s VK-2809 in people with nonalcoholic fatty liver disease (NAFLD) and elevated LDL-cholesterol found it delivered durable reductions in liver fat even four weeks post-treatment.

Millendo Therapeutics Inc. in April decided to scrap work altogether with livoletide in Prader-Willi syndrome after a phase IIb study fell short of statistical significance, but hope remains alive for – among others in the space – Soleno Therapeutics Inc., another recent newsmaker with once-daily diazoxide choline controlled-release tablets in PWS.

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Adaptimmune, Arrowhead, Assembly, Daiichi Sankyo, Enanta, Fortress, Idorsia, Janssen, Matinas, Treadwell, Viking.

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Alligator, Applied Molecular Transport, Axcella, Cognition, Cymabay, Durect, Intercept, Mycovia, Oncosec, Onxeo, Redhill, Urogen.

Strong top-line results from Immunovant Inc.’s phase IIa clinical trial of IMVT-1401 in treating moderate to severe generalized myasthenia gravis increased the competition with Momenta Pharmaceuticals Inc. and Argenx SE in the crowded anti-FcRn space.

Clinical updates, including trial initiations, enrollment status and data readouts and publications: 4D Pharma, Cardiol, Cerecor, Dermavant, Mycovia, Novartis, Oncolytics, Oncology Venture, Outlook, Silverback.

Now that Ovid Therapeutics Inc.’s and Takeda Pharmaceutical Co. Ltd.’s phase II study of soticlestat in children with Dravet syndrome (DS) or Lennox-Gastaut syndrome (LGS) has produced positive top-line data, Ovid is planning the drug’s phase III clinical trial while pricing a $50 million common stock offering.

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Astrazeneca, Bavarian Nordic, Bristol Myers Squibb, Byondis, Immunovant, Ipsen, Krystal, Mereo, Ovid, Takeda, Union.