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Home » Topics » Conferences, BioWorld Science

Conferences, BioWorld Science
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HIV virus cells
HIV/AIDS

Coinfections and diversity paint the many shades of HIV cure

July 22, 2025
By Mar de Miguel
No Comments
We all look different to HIV, a virus that destroys the immune system. The defensive cells record every interaction with foreign agents, infections from viruses and bacteria, but also with mechanisms occurring within the body, such as microbiome metabolism, the effects of aging, or the development of diseases. At a preconference session at the 13th IAS Conference on HIV Science (IAS 2025), scientists explained the interactions of different microorganisms with HIV.
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Illustration of antibodies attacking the thyroid
Endocrine/metabolic

Crinetics’ TSHR antagonist demonstrates efficacy in thyroid autoimmune disorders

July 21, 2025
No Comments
Graves disease (GD)-associated hyperthyroidism is an autoimmune disorder characterized by the presence of autoantibodies that stimulate the thyroid-stimulating hormone receptor (TSHR), leading to excessive production of thyroid hormones.
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Woman and molecular overlay
Endocrine/metabolic

Research shows d3-T has testosterone benefits without estradiol conversion

July 18, 2025
No Comments
In drug development, replacing hydrogen atoms with deuterium may help improve the pharmacokinetic profile without altering pharmacodynamic activity.
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Transmission electron micrograph of HIV-1 virus particles
HIV/AIDS

IAS 2025: Cheat, parasitize, break the virus – fresh ideas fuel HIV research

July 18, 2025
No Comments
There is still no effective vaccine or cure for HIV. Scientists are considering options ranging from longer-term antiretroviral therapy (ART) that space out injections by several years to long-lasting pre-exposure prophylaxis (PrEP) that acts as a vaccine while immunization is achieved. What else can be done? The “Innovations in HIV virology: Translating discoveries into novel therapies” symposium in basic science at the 13th IAS Conference on HIV Science (IAS 2025), which took place from July 13 to 17, 2025, in Kigali, Rwanda, showcased some of the new ideas that the scientific community are developing.
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Endocrine/metabolic

RT-114 robotic capsule matches injectable PG-102 in preclinical study

July 16, 2025
No Comments
Incretin-based therapies have demonstrated substantial efficacy in the treatment of metabolic diseases such as obesity and type 2 diabetes but the need for frequent injections remains a major barrier to patient adherence and comfort.
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Transmission electron micrograph of HIV-1 virus particles
HIV/AIDS

IAS 2025: All eyes still on the HIV reservoir

July 16, 2025
By Mar de Miguel
No Comments
While people living with HIV can lead virtually normal lives thanks to antiretroviral therapy (ART), HIV persists in a latent state within cellular reservoirs that scientists do not know how to eliminate. “Transcription is a critical step in the viral life cycle. … But there are currently no drugs suppressing HIV transcription, and that may be one of the reasons why current antiretroviral therapy is not curative,” Melanie Ott told the audience at the 13th IAS Conference on HIV Science this week in Kigali, Rwanda.
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Endocrine/metabolic

Improved muscle health and glucose metabolism shown with JUV-161

July 15, 2025
No Comments
Obesity and diabetes are known risk factors for sarcopenia. Insulin resistance that occurs during type 2 diabetes promotes impaired synthesis of muscle protein and muscle breakdown. Juvena Therapeutics Inc. has presented data at ENDO 2025 conference for JUV-161, a novel secreted protein that induces insulin sensitization, regarding its impact on blood glucose and muscle in mice with type 2 diabetes (db/db mice).
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Endocrine/metabolic

Marea’s novel GH receptor antagonist outperforms existing treatments for acromegaly

July 15, 2025
No Comments
Acromegaly is a rare, chronic endocrine disorder characterized by excessive secretion of growth hormone (GH), most commonly resulting from a benign pituitary adenoma.
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Fallopian tubes, ovaries and uterus
Genitourinary/sexual function

ARV-110 ameliorates metabolic and renal impairment in polycystic ovary syndrome

July 15, 2025
No Comments
Polycystic ovary syndrome is a common endocrine disorder in women of reproductive age and characterized by obesity, insulin resistance and renal injury.
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Feet and scale
Endocrine/metabolic

JUV-112 induces weight loss through a non-appetite-suppressing mechanism

July 15, 2025
No Comments
GIPR/GLP-1R-targeting agents have demonstrated significant efficacy in appetite suppression and weight reduction; however, their adverse effect profiles and tolerability issues highlight the need for alternative or complementary therapeutic strategies in the management of obesity. Researchers from Juvena Therapeutics Inc. reported on the preclinical profile of JUV-112, discovered using Juvena’s proprietary JuvNET platform.
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