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Home » Topics » Deals and M&A, BioWorld Science

Deals and M&A, BioWorld Science
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Scientists shaking hands in the lab
Drug design, drug delivery & technologies

With new leadership, Creyon enters a $1B-plus deal with Lilly

May 6, 2025
By Lee Landenberger
Less than a week after announcing it had a new CEO, privately held Creyon Bio Inc. began a licensing and research partnership with Eli Lilly and Co. Creyon is getting $13 million up front and could bring in more than $1 billion in milestone payments. The two plan to find, develop and commercialize RNA-targeted oligonucleotide treatments for a range of diseases.
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Conceptual 3D illustration showing degradation of motor neuron
Neurology/psychiatric

Alchemab and Lilly sign licensing agreement for ATLX-1282

May 6, 2025
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Alchemab Therapeutics Ltd. has entered into a licensing agreement with Eli Lilly and Co. for ATLX-1282, Alchemab’s first-in-class IND-ready program targeting a novel receptor and mechanism for amyotrophic lateral sclerosis (ALS) and other neurodegenerative conditions.
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Health professional pointing at handshake icon among other medical icons
Immuno-oncology

Abtherx and Rondo collaborate on antibody discovery

April 24, 2025
Abtherx Inc. has signed a technology license agreement with Rondo Therapeutics with the aim of accelerating Rondo’s pipeline of bispecific antibodies. Rondo aims to advance the field of immuno-oncology, with a focus on treating solid tumors that fail to respond to current therapies.
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Endocrine/metabolic

Cyprumed, Merck ink $493M peptide pill licensing deal

April 16, 2025
By Nuala Moran
Oral peptide delivery specialist Cyprumed GmbH is about to find out if the high bioavailability of its tablet formulations seen in animal models will translate across to humans, after signing a $493 million license and option agreement with Merck & Co. Inc.
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Female hands holding heart on cardiogram
Endocrine/metabolic

Northstrive partners with Yuva Biosciences on obesity and cardiometabolic diseases

April 11, 2025
Northstrive Biosciences Inc., a subsidiary of PMGC Holdings Inc., has entered into a development and license agreement with Yuva Biosciences Inc. to discover and develop novel pharmaceutical treatments for obesity, type 2 diabetes and other cardiometabolic conditions using Yuva’s mitochondrial science-focused platform Mitonova, powered by AI.
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Women's health

Women’s health needs a ‘GLP-1 moment’ to attract investors

April 7, 2025
By Nuala Moran
“Men in general have been playing golf for a longer time – in those old boy networks we still haven’t tapped into.” It may seem far-fetched, but that is put forward as a reason for underinvestment in women’s health companies. The argument goes that women heading women’s health startups find it hard to raise money because their networks are weaker, making it harder to tap into investment networks.
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Doctor measuring patient's waist
Endocrine/metabolic

Novo Nordisk licenses Lexicon’s preclinical obesity drug in $1B deal

March 31, 2025
By Karen Carey
As companies continually search for next-generation obesity prospects, one of the leaders in the disease space, Novo Nordisk A/S, has obtained an exclusive license to a preclinical-stage, first-in-class, small-molecule inhibitor of Acyl-CoA synthetase 5 (ACSL5) developed by Lexicon Pharmaceuticals Inc.
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Bispecific antibodies with heavy chain in green and pink, light chain in blue and yellow
Immuno-oncology

Sotio exercises option to license Synaffix technology for ADC programs

March 14, 2025
Sotio Biotech AS is exercising an option under a license and option agreement to obtain a license to Synaffix BV’s technology to develop two bispecific antibody-drug conjugate (ADC) programs  for solid tumors.
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Inflammatory

Novartis adds Kyorin’s preclinical MRGPRX2 antagonist in $777M deal

March 5, 2025
By Tamra Sami
Kyorin Pharmaceutical Co. Ltd. has out-licensed its preclinical candidate, KRP-M223, and its back-up compounds to Novartis Pharma AG in a deal worth up to $777.5 million. Under the terms, Novartis gains an exclusive worldwide license to develop, manufacture and commercialize Kyorin-discovered KRP-M223.
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Illustration of T cells attacking tumor
Immuno-oncology

Ellipses Pharma licenses monoclonal antibody targeting CNTN4 from Genome & Co.

Feb. 11, 2025
Ellipses Pharma Ltd. has agreed to in-license global rights to GENA-104, a first-in-class immuno-oncology monoclonal antibody that targets CNTN4, from Genome & Co. Ltd. Targeting CNTN4 is a new approach that blocks the CNTN4-APP checkpoint interaction on T cells, promoting tumor cell killing, with potential use in cancers that respond poorly to conventional checkpoint inhibitors.
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