Janssen and Johnson & Johnson have divulged dihydropyrimidine derivatives reported to be useful for the treatment of hepatitis B virus (HBV) infections.
Etherna Immunotherapies NV has raised €39 million (US$39 million) in new financing as it pivots to an mRNA-platform strategy. It has added a couple of heavy hitters to its board and its roster of investors, indicating that the move has already gained traction in the marketplace.
The first randomized placebo-controlled trial assessing the effectiveness of the antiviral drug Tpoxx (tecovirimat) in treating monkeypox has begun in the U.K., with the first patients enrolled on Aug. 21.
The Project to Accelerate New Treatments for Tuberculosis is progressing two investigational tuberculosis combination treatment regimens into phase II trials under a joint development agreement.
It’s been a patchy year for vaccine specialist Valneva SE, in which it saw European orders for its delayed
COVID-19 vaccine dry up but then received a €90.5 million (US$92.1 million) investment from Pfizer Inc. as its Lyme disease vaccine entered phase III. The firm has now hit another setback after the U.S. Department of Defense decided not to take an option for a second year in contract to supply a Japanese encephalitis vaccine, Ixiaro.
Hansoh Pharmaceutical's Hansoh (Shanghai) Healthtech subsidiary has entered into an exclusive licensing and codevelopment agreement with the Global Health Drug Discovery Institute (GHDDI; Beijing Huayi Health Drug Discovery Institute) for exclusive worldwide rights to develop, manufacture and commercialize GDI-4405, an oral small-molecule SARS-CoV-2 3CL protease inhibitor.
A factor involved in the apoptosis cascade, caspase-6, has been identified as a target for interfering with the replication of coronaviruses in work by The University of Hong Kong scientists and their collaborators.
Griffith University has presented new compounds reported to be useful for the treatment of respiratory syncytial virus (RSV), influenza A, influenza B, influenza C and parainfluenza virus infections.
Regeneron Pharmaceuticals Inc.’s Inmazeb and Ridgeback Biotherapeutics LP’s Ebanga earned a ringing endorsement from the World Health Organization (WHO) in its first ever guideline on Ebola therapies. In releasing the guideline Aug. 19, WHO officials celebrated the fact that Ebola is no longer “a near certain killer” – provided treatment starts as soon as possible following diagnosis.
After nearly four decades as director of the U.S. NIH’s National Institute of Allergy and Infectious Diseases (NIAID), 81-year-old Anthony Fauci will be stepping down in December. He also announced Aug. 22 that he will be handing over the reins as chief of the NIAID Laboratory of Immunoregulation and as chief medical adviser to President Joe Biden.
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