Acadia Pharmaceuticals Inc. has described G protein-coupled receptor GPR88 agonists reported to be useful for the treatment of attention deficit hyperactivity disorder (ADHD), substance abuse and dependence, schizophrenia, Tourette syndrome, bipolar disorder, Huntington's disease, Alzheimer's disease and Parkinson's disease.
Factor Bioscience Inc. has been awarded a grant by the U.S. Department of Defense to develop next-generation cell therapy candidates using Factor's patented mRNA, cell-reprogramming, and gene-editing technologies.
Neuron23 Inc. has identified non-receptor tyrosine-protein kinase TYK2 (JH2 domain) inhibitors reported to be useful for the treatment of neurological disorders.
Guangzhou Fermion Technology Co. Ltd. has announced IND clearance by China’s National Medical Products Administration (NMPA) for FZ-008-145 to treat pain.
Alzheimer’s disease (AD) can be divided into five distinct subtypes based on protein expression levels measured in the cerebrospinal fluid (CSF). The subtypes were associated with different genetic risk factors and are likely to benefit from different treatment approaches.
Many clinicians, drug developers and the general public still “think of Alzheimer’s as a single disease entity, and that suggests that every patient needs to have the same medication,” Betty Tijms told BioWorld.
Keiferx LLC has expanded its exclusive licensing agreement with Georgetown University to advance the development of novel tyrosine kinase inhibitor (TKI) chemical entities for the treatment of multiple disease indications.
Researchers at Jiangsu Hengrui Medicine Co. Ltd., Shanghai Fourth People’s Hospital Affiliated Tongji University and Shanghai Senhui Pharmaceutical Co. Ltd. have divulged cyclopentyl adenosine derivatives reported to be useful for the treatment of chronic pain.