Discovery of KSQ-004, a Regnase-1/SOCS1 dual-edited human CRISPR/Cas9-engineered TIL therapy Nov. 25, 2021 No Comments
CDX-585, a novel bispecific antibody targeting ILT4 and PD-1 for cancer treatment Nov. 25, 2021 No Comments
A novel protein-engineered IL-12 shows efficacy without peripheral toxicity in animal models Nov. 24, 2021 No Comments
ALTA-002, a Toll-like receptor agonist antibody conjugate with promising antitumor activity in vivo Nov. 24, 2021 No Comments
SNS-101, an anti-VISTA antibody, potentiates anti-PD-1/PD-L1 antitumor immunity Nov. 24, 2021 No Comments
AL-009 shows antitumor efficacy both as monotherapy and in combination with anti-PD-L1 Nov. 22, 2021 No Comments
Replication stress response defects signature predicts ICB response in nonhypermutated cancers Nov. 19, 2021 No Comments
SGN-PDL1V, a PD-L1-directed ADC with activity in multiple tumor xenograft models Nov. 19, 2021 No Comments